Cancer researchers have identified a microRNA that acts as a prognostic biomarker of p53-like bladder cancers.
Cancer researchers have identified a microRNA that acts as a prognostic biomarker of p53-like bladder cancers. MicroRNAs (miRNAs) and short interfering RNAs (siRNA) comprise a class of about 20 nucleotides-long RNA fragments that block gene expression by attaching to molecules of messenger RNA in a fashion that prevents them from transmitting the protein synthesizing instructions they had received from the DNA.
MiRNAs resemble siRNAs of the RNA interference (RNAi) pathway, except miRNAs derive from regions of RNA transcripts that fold back on themselves to form short hairpins, whereas siRNAs derive from longer regions of double-stranded RNA. With their capacity to fine-tune protein expression via sequence-specific interactions, miRNAs help regulate cell maintenance and differentiation. Bladder cancers can be categorized into subtypes according to gene expression patterns. Original Link:https://www.biotechdaily.com/genomics-proteomics/articles/294774178/microrna-biomarker-identified-for-bladder-cancers.html