Month: July 2018

Metabolites fabricate during digestion of omega-3 fatty acids have been found to have anti-cancer properties, and their synthetic derivatives have the potential to be developed into potent chemotherapeutic drugs. Dietary omega-3 fatty acids, such as docosahexaenoic acid (DHA), have been shown to suppress tumor thickening across their conversion to epoxide metabolites. Alternatively, DHA is transformed […]

A team of molecular microbiologists has identified a mechanism by which certain bacteria specifically gram-negative pathogen Neisseria gonorrhoeae – avoid lysozyme demolition. Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase is an antimicrobial enzyme prefabricated by animals that form part of the intrinsic immune system. Lysozymes are omnipresent as the first line of immune patronage […]

A team of genomics researchers has expressed the development of a novel biological switching mechanism that authorizes control over the activity of the CRISPR/Cas9 gene-editing tool. CRISPR/Cas9 is considered as the cutting edge of molecular biology technology. Several applications of genome editing by CRISPR-Cas9 necessitate rigid regulation and Cas9 modification have been appropriately generated whose […]

Cancer researchers have identified a microRNA that acts as a prognostic biomarker of p53-like bladder cancers. Cancer researchers have identified a microRNA that acts as a prognostic biomarker of p53-like bladder cancers. MicroRNAs (miRNAs) and short interfering RNAs (siRNA) comprise a class of about 20 nucleotides-long RNA fragments that block gene expression by attaching to […]

A team of drug developers has chronicle a small molecule microarray-based approach that grants for unvarying low molecular weight compounds, including [U.S.] Food and Drug Administration-approved drugs, to be probed for binding to RNA motif libraries in a massively parallel format. Potential RNA drug earmark for small molecules are found throughout the human transcriptome, yet […]

Results of cryo-electron microscopy (cryo-EM) studies revealed the molecular mechanism by which the Plasmodium vivax malaria parasite binds to and invades red blood cells in the human host. TfR1-deficient erythroid cells were refractory to invasion by P. vivax, and anti-PvRBP2b (P. vivax reticulocyte-binding protein 2b) monoclonal antibodies inhibited reticulocyte binding and blocked P. vivax invasion […]

The production of cooking oils is also awaited to swell. Currently, Tanzania imports 60 percent of cooking oils despite having a vast potential of sunflower seeds, according to a Bank of Tanzania report of 2017. The research institution facilitates the planting of the new high oleic four hybrids — Michel, Archeo, Ancilla, and Soleado — […]

A new therapeutic approach for killing tumor cells simultaneously blocks both the PARP and RAD52 DNA repair pathway has. The aptness of cancer cells to convalesce from treatment with PARP inhibitors (PARPis) stipulate that more burly and rapid elimination of BRCA-deficient tumor cells is statutory to prevent the time-dependent emergence of PARPi-resistant or stroppy clones. […]